October 23
September 23
August 23
July 23
February 23
December 22
November 22
September 22
Gaia is a new PhD candidate in Traslational Medicine! She got out of the selection as 3nd out of many applicants and she will develop a project in collaboration with Elisa Borghi’s lab.
August 22
July 22
June 22
Francesco won the Ranzi award! Francesco’s master thesis on the generation and characterization of Drosophila mutants of the glycosylation gene Tusc3 was awarded the Ranzi prize for developmental biology.
April 22
Giulia graduated! Giulia defended her Master thesis on the characterization of Drosophila Cathepsin F as a model of Type B Kufs disease earning top marks and honors!
March 22
December 21
Gaia graduated! Gaia defended her Master thesis on the nutritional effects on the fitness of fly models of CDGs earning top marks and honors!
October 21
Our first PRIN! The lab got awarded a PRIN (Progetti di interesse nazionale – National Interest Projects) grant together with the group of MG Giansanti (CNR Rome) and G Callaini (Uni Siena). We are elated as this is the first time and PRIN is the only basic science grant in Italy (~10% funding rate). Cheers to 3 years support for SNAP29-related science!!
September 21
Giuliana is a new PhD candidate in Molecular and Cellular Biology! She got out of the selection as 2nd out of 63 applicants and she will continue her project in collaboration with Simona Polo’s lab
September 21
July 21
Simona is a new PhD candidate in Translational Medicine! She got out of the selection as 5th out of 63 applicants and she will continue her project in collaboration with Valentina Massa
April and June 21
Simona and Francesco graduated! Welcome Dr. Totaro and Lavezzari!
18/5/21
Miriam PhD paper is out! In it we study autophagy and V-ATPase in a genetic model of glioma in Drosophila!
31/3/21
A nice collaboration study with the group of Valentina Massa! We explored the microbiome of Drosophila as a possible model of rare disease!
14/1/21
The last paper of the Snap29 trilogy by Elena and others in the lab has been accepted in Frontiers in cell and developmental biology! In it, we describe the role of Snap29 in trafficking at the ER and Golgi compartments.
8/12/20
A nice collaboration with the group of Andrea Bassi at Polimi. Here we developed a nifty light sheet microscope connected to a microfluidic device for automated dual-color imaging of Drosophila embryos! Link
20/09/20
China presented her work at MyDev2020, the yearly meeting we co-organize with other labs interested in development in Milan, and got an honorable mention!
28/07/20
The great work of Antonio, started in the lab of Hamed Jafar-Nejad and completed in the lab is finally out! Read about Dpp regulation and glycosylation and how this is relevant to patients affected by congenital disorders of glycosylation. Link
12/12/19
12/10/19
20/07/19
18/07/19
Great collaborative work with the group of Valentina Massa UNIMI and others. In which we model aspects of the interactions that might be disrupted in Cornelia de Lange syndrome https://www.nature.com/articles/s41419-019-1792-x
05/07/19
A nice collaboration paper with the group of Stefano Biffo at INGM UNIMI. All about the phenotypic effects of ribosome assembly regulation by eIF6. If you can’t read it at https://www.sciencedirect.com/science/article/pii/S0012160618307966?via%3Dihub pls write to me for access.
28/6/19
We published a technical paper about analyzing ESCRT complexes in Drosophila. First work of talented master student Marco Gualtieri, now a PhD student at Pasteur Institute in Paris. if you cannot read it at https://link.springer.com/protocol/10.1007%2F978-1-4939-9492-2_2 shoot me an email and I’ll send you a direct link!
1/6/19
We are now part of the ITN SAND investigating unconventional secretion in neurodegeneration!
We have been awarded an European MSCA-ITN mega grant as the Italian unit of a consortium that aims at elucidating the role of trafficking in neurodegenation diseases. Read the details (in Italian) http://lastatalenews.unimi.it/marie-s-curie-innovative-training-networks-finanziati-quattro-progetti-statale. We are seeking an talented PhD student for enrollment in the fall. Details will come soon!
13/2/19
Antonio Galeone wins a Marie Curie Reintegration Fellowship to work in the lab on modeling rare CDG disease in fly! CONGRATS!!
Some press release about recent papers (in italian)
6/2/19
Paper 2 on V-ATPase and oncosomes is out now in EBioMedicine!
https://www.ebiomedicine.com/article/S2352-3964(19)30059-3/fulltext
5/2/19
Paper on V-ATPase deregulation in Glioblastoma is out now in EBioMedicine. Great teamwork with Valentina Vaira at Policlinico, Milano. https://www.ebiomedicine.com/article/S2352-3964(19)30058-1/fulltext
Press release (in Italian)
16/12/18
Paper on modeling of CEDNIK in zebrafish in Scientific Reports! Congrats Valeria! Hera the link to read it!
10/10/18
Sugars and damaged lysosomes with a dash of autophagy is what one needs to prevent neurodegeneration!
Read it here
19/7/18
A tour the force review of non canonical Notch signaling in Molecular Mechanisms of Notch Signaling Book!
Read it here
29/6/18
A small contribution in a nice story about Autophagy and Alzheimer disease in Molecular Psychiatry!
Read it here
21/3/18
Our latest review on the many talents of SNARE protein Snap29, one of our favorite molecules, is out now in Cell Stress!
Read it here
8/3/18
Today’s International Women’s day. Women are the large of majority among the scientists in the lab. Let’s support them in removing every obstacle to science careers they deserve!
7/3/18
Thomas is co-organizing a EMBL alumni science and networking event in #Milan. Please register for free here and join us on May 3-4, 2018!
21/2/18
Thomas got interviewed by the newspaper “La Stampa” about the designation of Iain Mattaj as suitable future director of Human Technopole. Read it here (in Italian): Intervista La Stampa 21 Febbraio 2018.top
10/12/18
Our department won the 1st Italian Department of Excellence call from the ministry of research and education. >8M€ coming our way for the next 5 years! Thomas was part of the project writing team.
!!Happy Holidays!!
13/12/17
Francesca and Marco defended their master thesis work at UNIMI! Well done!
30/11/17
We won a 5-year grant from the AIRC! Support them so they can support us and other Italian scientists!
October-December 2017
Valeria, Valentina and Victor defended brilliantly their PhD work at SEMM!
Congratulations!
20/10/17
We won a 3-year grant from the Wordwide Cancer Research Charity!
Read about them here.
05/10/17
Radio3scienza interviewed Thomas about the Cryo-EM Nobel.
Listen to the podcast here (in Italian).
04/10/17
New York Times Op-ed by Thomas’ former boss Professor David Bilder of UC Berkeley.
Read his passionate defense of Drosophila’s role in biomedical research!
04/10/17
The 2017 Nobel for Chemistry is awarded to the scientists developing Cryo-EM.
Read Thomas’ comments about the Nobel for Focus.it (in italian)
26/08/17
Our latest review on ESCRT genes and developmental signaling is out in “Seminars in Cell and Developmental Biology”
Read about the the wonders of these great cellular machines that keep us alive and healthy every hour of the day (and night) at: http://www.sciencedirect.com/science/article/pii/S1084952116305031?via%3Dihub
08/05/17
The Vaccarilab is featured at the final event of “Deploy Your Talent 2017”! DYT2017 is a program of Fondazione Sodalitas to engage in STEM high school students in the Milan area. Elena Morelli in the lab taught the class about how our lab works and how to choose a career path in science. We hosted the students in the lab for a 1-day tutorial full of enthusiasm and fun –
03/05/17
Follow and join Thomas’ (@vaccart) conversation about science on Twitter
01/05/17
Check out Thomas’ science divulgation articles (Italian) for Scienza in rete