{"id":26,"date":"2017-05-09T16:24:11","date_gmt":"2017-05-09T16:24:11","guid":{"rendered":"http:\/\/vaccarilab.unimi.it\/?page_id=26"},"modified":"2023-12-27T14:15:27","modified_gmt":"2023-12-27T14:15:27","slug":"key-publications","status":"publish","type":"page","link":"https:\/\/www.vaccarilab.unimi.it\/index.php\/key-publications\/","title":{"rendered":"Publications and Teaching"},"content":{"rendered":"

All Publications from Medline<\/a><\/h3>\n

Key Papers<\/h3>\n

Pandey A, Galeone A, Han SY, Story BA, Consonni G, Mueller WF, Steinmetz LM, Vaccari T<\/span>, Jafar-Nejad H. (2023). Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila.
\nNature Communications<\/strong> doi: 10.1038\/s41467-023-40910-w<\/a>.<\/p>\n

Frappaolo A, Karimpour-Ghahnavieh A, Cesare G, Sechi S, Fraschini R, Vaccari T<\/span>, Giansanti MG (2022). GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila.
\nCell Death and Disease<\/strong> doi: 10.1038\/s41419-022-05438-9<\/a>.<\/p>\n

Fajner V, Giavazzi F, Sala S, Oldani A, Martini E, Napoletano F, Parazzoli D, Cesare G, Cerbino R, Maspero E,\u00a0Vaccari T*<\/span>, Polo S (2021). Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles. Nature<\/strong> Communications<\/strong> doi: 10.1038\/s41467-021-25809-8<\/a><\/p>\n

\n

Formica M, Storaci AM, Bertolini I, Carminati F, Kn\u00e6velsrud H, Vaira V, Vaccari T<\/span> (2021). V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis.
\nAutophagy<\/strong> doi: 10.1080\/15548627.2021.1918915<\/a>.<\/p>\n

Morelli E, Speranza E, Pellegrino E, Beznoussenko G, Carminati F, Garr\u00e9 M, Mironov AA, Onorati M and Vaccari T<\/span> (2021). The SNARE protein SNAP29 is a new regulator of vesicle transport at the Golgi Apparatus and Endoplasmic Reticulum.\u00a0Frontiers in Cell and Developmental Biology <\/b>doi: 10.3389\/fcell.2021.637565<\/a><\/p>\n

Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori, Storaci AM, Formica M, Bosari S, Cairoli M, Ottobrini L, Vaccari T*<\/span>, Vaira V (2019). A Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivoSpecific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo. EBioMedicine\u00a0<\/strong>https:\/\/doi.org\/10.1016\/j.ebiom.2019.01.052<\/a><\/p>\n

Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G & Vaccari T<\/span> (2019). A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Scientific Reports\u00a0<\/strong>\u00a0<\/a>https:\/\/www.nature.com\/articles\/s41598-018-37780-4<\/a><\/p>\n

Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garr\u00e8 M, Morelli E, Vaccari T<\/span>, Poletti A. (2018).\u00a0Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.\u00a0Autophagy<\/span><\/strong>\u00a018:1-21. doi: 10.1080\/15548627.2018.1535292<\/a><\/p>\n<\/div>\n

Morelli E, Mastrodonato V, Beznoussenko G, Mironov AA, Tognon E,\u00a0Vaccari T<\/u>\u00a0(2016). An essential step of kinetochore formation controlled by the SNARE protein Snap29.\u00a0The EMBO Journal\u00a0<\/strong>35(20): 2223-37<\/a>.\u00a0PDF-EMBOJ-2016<\/a><\/p>\n

Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F,\u00a0Vaccari T<\/u>\u00a0(2016). Control\u00a0of lysosomal biogenesis and\u00a0Notch-dependent\u00a0tissue patterning by\u00a0components\u00a0of\u00a0the TFEB\/V-ATPase axis in\u00a0Drosophila melanogaster.\u00a0Autophagy<\/strong>\u00a012(3): 499-514<\/a>.\u00a0PDF-Aut-2016<\/a><\/p>\n

Morelli E, Ginefra P, Mastrodonato V, Beznoussenko G, Rusten TE, Bilder D, Stenmark H, Mironov AA,\u00a0Vaccari T<\/u>\u00a0(2014). Multiple functions of the SNARE protein Snap29 in autophagy, endocytic and exocytic trafficking during epithelial formation in Drosophila.\u00a0Autophagy\u00a0<\/strong>10(12): 2251-68<\/a>.\u00a0PDF-Aut-2014<\/a><\/p>\n

Kobia F, Duchi S, Deflorian G,\u00a0Vaccari T<\/u>\u00a0(2014). Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling.\u00a0Molecular Oncology<\/strong>\u00a0pii: S1574-7891(13): 00160-9<\/a>.\u00a0PDF-Mol Oncol-2014<\/a><\/p>\n

Tognon E, Wollscheid N, Cortese K, Tacchetti C,\u00a0Vaccari T\u00a0<\/u>(2014). ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila.\u00a0PLoS ONE<\/strong>\u00a09(4): e93987<\/a>.\u00a0PDF-PlosONE-2014<\/a><\/p>\n

Petzoldt AG, Gleixner EM, Fumagalli A,\u00a0Vaccari T*\u00a0<\/u>and Simons M (2013). Activation of the proton pump, V-ATPase, triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium.\u00a0Disease Models & Mechanisms\u00a0<\/strong>6(3): 689-700.<\/a>\u00a0PDF-PlosONE-2014<\/a>\u00a0*co-corresponding.<\/p>\n

Vaccari T*<\/u>, Duchi S, Cortese K, Tacchetti C, Bilder D (2010). The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor.\u00a0Development\u00a0<\/strong>137 (11): 1825-32<\/a>. PDF-Develop-2010<\/a>\u00a0*co-corresponding<\/p>\n

Key Reviews + Technicals<\/h3>\n
\n

Smeele PH, Vaccari T<\/span>. (2022) Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis. Semin Cell Dev Biol. 2022 Mar 4:S1084-9521(22)00063-5. <\/strong>doi: 10.1016\/j.semcdb.2022.02.024<\/a>.<\/p>\n

Gualtieri M, Vaccari T<\/span>. (2019) Genetic and Cell Biology Methods to Study ESCRTs in Drosophila melanogaster. Methods Mol Biol<\/span>. 1998:13-29.<\/strong> doi: 10.1007\/978-1-4939-9492-2_2.<\/a><\/p>\n

Mastrodonato V, Morelli E,\u00a0Vaccari T<\/span>. (2018) How to use a multipurpose SNARE: The emerging role of Snap29 in cellular health. Cell Stress <\/span>2(4):72-81.<\/strong> doi: 10.15698\/cst2018.04.130<\/a>.<\/p>\n

Alfred V, Vaccari T<\/span>. (2018) \u00a0Mechanisms of Non-canonical Signaling in Health and Disease: Diversity to Take Therapy up a Notch?\u00a0Adv Exp Med Biol<\/span>. 1066:187-204. <\/a><\/strong>doi: 10.1007\/978-3-319-89512-3_9<\/a>.<\/p>\n<\/div>\n

Horner D, Pasini ME, Beltrame M, Mastrodonato V, Morelli E,\u00a0 Vaccari T.<\/span> (2017).<\/b> ESCRT genes in developmental signaling. Seminars in Cell & Developmental Biology<\/b> <\/a>\u00a0pii: S1084-9521(16)30503-1.\u00a0<\/i><\/p>\n

Tognon E,\u00a0Vaccari T.<\/span> (2014). Immunohistochemical tools and techniques to visualize Notch in Drosophila melanogaster. Methods Mol Biol<\/span>. 2014;1187:63-78.<\/strong> doi: 10.1007\/978-1-4939-1139-4_5.<\/a><\/p>\n

Rusten TE,\u00a0Vaccari T,<\/u>\u00a0Stenmark H (2012). Shaping Development with ESCRTs.\u00a0Nature Cell Biology<\/strong>\u00a022;14(1): 38-45<\/a>.\u00a0PDF-Nat Cell Biol-2012<\/a><\/p>\n

Undergraduate courses thought by Thomas<\/h3>\n
    \n
  1. Biologia Generale e Ambientale con elementi di Istologia<\/span><\/a>. Corso di laurea triennale in Scienze Naturali. 2018- ongoing (Fall Semester).<\/li>\n
  2. Advanced Molecular and Cellular Biotechnology<\/span><\/a>. Master of Science in Molecular Biotechnology and Bioinformatics – 2018- ongoing (Spring Semester)<\/li>\n
  3. Cell Population Dynamics<\/span><\/a>. Master of Science in Quantitative Biology – 2022- ongoing (Spring Semester)
    \n

    Graduate mentoring by Thomas<\/h3>\n

    Thomas is part of the faculty of the Molecular and Cellular Biology PhD program<\/a> of the University of Milan<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    All Publications from Medline Key Papers Pandey A, Galeone A, Han SY, Story BA, Consonni G, Mueller WF, Steinmetz LM, Vaccari T, Jafar-Nejad H. (2023). Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila. … Continued<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-feature.php","meta":{"kt_blocks_editor_width":"","footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/pages\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":25,"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":769,"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/pages\/26\/revisions\/769"}],"wp:attachment":[{"href":"https:\/\/www.vaccarilab.unimi.it\/index.php\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}